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Clinical and Laboratory Standards Institute the pathogen box
The Pathogen Box, supplied by Clinical and Laboratory Standards Institute, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/the+pathogen+box/the+pathogen+box/pm38699477-55-15-28
Average 90 stars, based on 1 article reviews
the pathogen box - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Concentration Assay:

Article Title: NmrB ( AN9181 ) expression is activated under oxidative stress conditions acting as a metabolic repressor of Aspergillus nidulans .
Article Snippet: The composition of the trace elements, vitamins, and nitrate salts has been described previously (Kafer, 1977). .. The Minimal Inhibitory Concentration (MIC) for fungal growth inhibition of IDQ, initially acquired from The Pathogen Box (www. pathogenbox.org/), was defined following the standard methodology implemented by the Clinical and Laboratory Standards Institute (CLSI, 2018). .. The compound’s antifungal activity was analyzed by serial dilutions using MIC assay (0 to 25 μM) in MOPS buffered RPMI 1640 medium (Sigma-Aldrich), pH 7.0 in 96-wells plates.

Inhibition:

Article Title: NmrB ( AN9181 ) expression is activated under oxidative stress conditions acting as a metabolic repressor of Aspergillus nidulans .
Article Snippet: The composition of the trace elements, vitamins, and nitrate salts has been described previously (Kafer, 1977). .. The Minimal Inhibitory Concentration (MIC) for fungal growth inhibition of IDQ, initially acquired from The Pathogen Box (www. pathogenbox.org/), was defined following the standard methodology implemented by the Clinical and Laboratory Standards Institute (CLSI, 2018). .. The compound’s antifungal activity was analyzed by serial dilutions using MIC assay (0 to 25 μM) in MOPS buffered RPMI 1640 medium (Sigma-Aldrich), pH 7.0 in 96-wells plates.



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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Image Search Results


Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard antimalarial drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.

Journal: Scientific Reports

Article Title: Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates

doi: 10.1038/s41598-025-85643-6

Figure Lengend Snippet: Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard antimalarial drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.

Article Snippet: To accelerate the development of new chemotherapeutic agents for the treatment of drug-resistant malaria parasites, institutions such as Medicines for Malaria Venture (MMV) are collaborating with GlaxoSmithKline and St. Jude Children’s Research Hospital to promote research and the rapid development of new antimalarial agents (malaria or pathogen box) .

Techniques: Concentration Assay

Summary of  antimalarial  drug resistance and the associated genes in laboratory P. falciparum strains. Adapted and modified from a previous study <xref ref-type= 53 ." width="100%" height="100%">

Journal: Scientific Reports

Article Title: Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates

doi: 10.1038/s41598-025-85643-6

Figure Lengend Snippet: Summary of antimalarial drug resistance and the associated genes in laboratory P. falciparum strains. Adapted and modified from a previous study 53 .

Article Snippet: To accelerate the development of new chemotherapeutic agents for the treatment of drug-resistant malaria parasites, institutions such as Medicines for Malaria Venture (MMV) are collaborating with GlaxoSmithKline and St. Jude Children’s Research Hospital to promote research and the rapid development of new antimalarial agents (malaria or pathogen box) .

Techniques: Modification

Effects of auranofin (E-H-05) on E. histolytica trophozoite proliferation and E. invadens cyst formation. (A) Encystation assay. Encystation-inducing culture was treated with auranofin immediately after induction (0–72 h). Encystation-inducing culture was treated with auranofin 48 h after induction. Flow cytometric analysis was performed 72 h after induction (48–72 h). (B) Trophozoite proliferation assay. The total cell number counted is indicated in the upper left corner. Representative data are shown from three experiments in (A,B) , respectively.

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: A Flow Cytometry Method for Dissecting the Cell Differentiation Process of Entamoeba Encystation

doi: 10.3389/fcimb.2018.00250

Figure Lengend Snippet: Effects of auranofin (E-H-05) on E. histolytica trophozoite proliferation and E. invadens cyst formation. (A) Encystation assay. Encystation-inducing culture was treated with auranofin immediately after induction (0–72 h). Encystation-inducing culture was treated with auranofin 48 h after induction. Flow cytometric analysis was performed 72 h after induction (48–72 h). (B) Trophozoite proliferation assay. The total cell number counted is indicated in the upper left corner. Representative data are shown from three experiments in (A,B) , respectively.

Article Snippet: Auranofin (>98% purity) (which is identified as E-H-05 in the Pathogen Box) was also purchased from Sigma-Aldrich, dissolved in DMSO to 10 mM and dispensed into 50 μL aliquots for storage at −30°C.

Techniques: Proliferation Assay